Prof. Dr. Kai Tittmann

Professor of Molecular Enzymology

Since 2014: Professor of Molecular Enzymology, Georg-August-University, Göttingen (Germany)

2008-2014: Professor of Bioanalytics, Georg-August-University, Göttingen (Germany)

2006: Associate Guest Professor, Ben-Gurion-University of the Negev, Beer-Sheva, IL

2003: Invited Research Scientist at Rutgers University, Newark, NJ, USA

2003-2008: Jun.-Prof. of Molecular Enzymology, Institute for Biochemistry, MLU Halle-Wittenberg, Halle/Saale, (Germany)

2001-2002: Postdoc, Institute for Biochemistry, MLU Halle-Wittenberg, Halle/Saale (Germany)

2000: Dr. rer. nat., Martin-Luther-University, Halle/Saale (Germany)

1996: Diploma (Biochemistry), Martin-Luther-University, Halle/Saale (Germany)

Awards

2014: Peter Yates Lecture, University of Toronto

2005: Prize for excellent basic research at Saxony-Anhalt

2001: Dorothea-Erxleben-Prize (best doctoral thesis)

Major Research Interests
The central research topic of our department is the analysis of molecular reaction mechanisms of enzymes as nature's chemical catalysts. In this context, we study enzymes with vitamin-derived cofactors, with metal ions, and Schiff base-forming enzymes. A particular focus is laid on the structural and kinetic characterization of enzymatic reaction intermediates by high-resolution X-ray crystallography, steady-state and transient kinetic methods, NMR spectroscopy and theoretical studies. Knowledge about the reaction mechanism is exploited to redesign enzymes for biocatalytic applications and for drug design.

Homepage Department/Research Group:
http://www.uni-goettingen.de/de/abteilung/207823.html

ORCID: 0000-0001-7891-7108